CT理论与应用研究2025，Vol.34Issue(1)：17-22,6.DOI:10.15953/j.ctta.2024.187
右冠状动脉起自左冠窦患者的CT解剖及CT-FFR特征与临床症状的相关性研究
Correlation of Computed Tomography Angiography and Fractional Flow Reserve Features with Symptoms in Patients with Right Coronary Artery Originating from the Left Coronary Sinus
摘要
Abstract
Objective:This study aimed to explore the association between the anatomical and hemodynamic characteristics and the clinical symptoms in patients with the origin of the right coronary artery from the left coronary sinus(AORL)using coronary computed tomography angiography(CCTA)and CT fractional flow reserve(CT-FFR).Methods:A retrospective analysis was conducted on 151 patients with AORL detected by CCTA between January 2018 and December 2023 at our hospital.Patients were divided into the symptomatic(n=87)and asymptomatic(n=64)groups.CCTA images were used to compare anatomical differences of the RCA between both groups.CT-FFR values were measured and compared at 3 cm from the RCA ostium.Results:There were significant statistical differences between both groups regarding the RCA ostial morphology,origin angle,proximal lumen stenosis rate,length of the stenotic segment,and its relation to the pulmonary artery.The angle at the RCA ostium showed moderate correlation with clinical symptoms(r=0.566),whereas the ostial shape,proximal lumen stenosis rate,length of the stenotic segment,and relation to the pulmonary artery showed low correlation with symptoms.CT-FFR values were(0.94±0.02)and(0.97±0.01)for the symptomatic and asymptomatic groups,respectively,with a significant difference and moderate correlation with clinical symptoms(r=0.594).Conclusion:In patients with AORL,anatomical features,such as a slit-like RCA ostium,smaller origin angle,proximal lumen stenosis,long stenotic segment,and course between large arteries,are associated with clinical symptoms.Changes in CT-FFR are related to cardiovascular symptoms;however,further research is needed to determine measurement methods and critical values.关键词
CT血管成像/冠状动脉变异/血流储备分数Key words
computed tomography angiography/coronary artery variation/fractional flow reserve分类
医药卫生引用本文复制引用
毛亮,王小强,刘晓龙,翟宁,陈月芹..右冠状动脉起自左冠窦患者的CT解剖及CT-FFR特征与临床症状的相关性研究[J].CT理论与应用研究,2025,34(1):17-22,6.基金项目
济宁市重点研发计划(基于冠状动脉CTA及CT-FFR对冠状动脉先天变异患者发生不良心血管事件的预测研究(2024YXNS061)) （基于冠状动脉CTA及CT-FFR对冠状动脉先天变异患者发生不良心血管事件的预测研究(2024YXNS061）
济宁市重点研发计划(多模态心脏磁共振对射血分数保留的心力衰竭诊断及预后评估价值的研究(2022YXNS011)) （多模态心脏磁共振对射血分数保留的心力衰竭诊断及预后评估价值的研究(2022YXNS011）
济宁市重点研发计划(基于多模态CMR和生物标记物探究慢性心力衰竭患者预后不良的危险因素及预测模型的构建(2023YXNS142)). （基于多模态CMR和生物标记物探究慢性心力衰竭患者预后不良的危险因素及预测模型的构建(2023YXNS142）
