现代食品科技2025，Vol.41Issue(1)：81-88,8.DOI:10.13982/j.mfst.1673-9078.2025.1.1514
环二肽Cyclo(Leu-Pro)对植物乳杆菌的促生长作用
Growth-promoting Effect of Cyclic Dipeptide Cyclo(Leu-Pro)on Lactobacillus plantarum
摘要
Abstract
In this study,it's the effect of Cycle(Leu Pro)on the growth of Lactobacillus plantarum was investigated.Lactobacillus Plantarum T1 was used as the research object,and high-performance liquid chromatography(HPLC)was used to preliminarily characterize and quantify the Cyclo(Leu-Pro)in the fermentation broth of Lactobacillus Plantarum T1.Lactobacillus Plantarum T1 was respectively inoculated in the MRS broth medium without or with different mass concentrations(0.5,1,5,10 μg/mL)of Cyclo(Leu-Pro)for 18 h.The growth curves and viable bacterial counts of Lactobacillus plantarum T1 under different culture conditions were determined by the 96-well method and plate counting method.The results showed that Cyclo(Leu-Pro)at different mass concentrations had significant growth-promoting effects on the growth of Lactobacillus plantarum T1,among which,1 μg/mL Cyclo(Leu-Pro)had the greatest growth-promoting effect and could increase the viable counts to 8.73×1010 CFU/mL,which was an order of magnitude higher than the control.Under different stress conditions,1 μg/mL Cyclo(Leu-Pro)could shorten the lag period and increase the growth rate of Lactobacillus plantarum T1,and its viable count and biomass increased significantly(P<0.05).In summary,Cyclo(Leu-Pro)promoted the growth of Lactobacillus plantarum T1 and enhanced its stress resistance.This will favor the application of Lactobacillus plantarum T1 as a starter in the field of food fermentation.关键词
环二肽Cyclo(Leu-Pro)/植物乳杆菌/促生长/增殖Key words
cyclo(Leu-Pro)/Lactobacillus plantarum/growth promotion/proliferation引用本文复制引用
谭旭,吴忠坤,夏迪,高宁,王丽,高瑶,郭新梅,刘学聪,王远亮..环二肽Cyclo(Leu-Pro)对植物乳杆菌的促生长作用[J].现代食品科技,2025,41(1):81-88,8.基金项目
国家自然科学基金项目(31701606) （31701606）
淮安市重点实验项目(HA202310) （HA202310）
