食品工业科技2025,Vol.46Issue(6):438-447,10.DOI:10.13386/j.issn1002-0306.2024040445
天麻改善失眠作用机制及产品开发研究进展
Mechanism and Product Development of Gastrodia elata Blume for Improving Insomnia Research Progress
摘要
Abstract
Insomnia,a prevalent sleep disorder,may impact individuals'emotional health,lead to immune system problems,and increase the chance of developing chronic illnesses like diabetes and cardiovascular disease.As a type of medication and food homologous substance,Gastrodia elata's primary active ingredient,extract,and its byproducts demonstrate beneficial effects in treating insomnia.Though there is currently no comprehensive description,research on how Gastrodia elata's active ingredients can alleviate insomnia advances significantly.Thus,this review systematically delineates the pathophysiological mechanisms underlying insomnia.Secondly,it reviews the effects of the active ingredients in Gastrodia elata on improving insomnia,including regulating the biological clock,balancing the release of neurotransmitters,the expression of inflammatory factors,regulating the hypothalamus-pituitary-adrenal(HPA)axis,and modulating intestinal flora.Additionally,the paper looks at the current market for sleep aids that contain Gastrodia elata as a main ingredient.The objective provides basis for the research and development of Gastrodia elata.关键词
天麻/失眠机制/活性成分/产品开发/研究进展Key words
Gastrodia elata/insomnia mechanism/active ingredient/product development/research progress分类
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胡芙蓉,王昱涵,向琴,唐菁雯,贺思桥,耿敬章,娄在祥..天麻改善失眠作用机制及产品开发研究进展[J].食品工业科技,2025,46(6):438-447,10.基金项目
秦巴生物资源与生态环境国家重点实验室(培育)"市校共建"专项(SXC-2106) (培育)
陕西省教育厅重点科学研究计划项目(23JY018) (23JY018)
陕西省秦创原"科学家+工程师"队伍建设项目(2023KXJ-203) (2023KXJ-203)
陕西理工大学秦巴食品资源开发利用科技创新团队科研专项(SLGNL202406). (SLGNL202406)