食品科学2025，Vol.46Issue(6)：392-401,10.DOI:10.7506/spkx1002-6630-20240930-238
益生菌在改善老年人精神健康中的研究进展
Research Progress on Probiotics in Improving Mental Health of Older Adults
摘要
Abstract
As the global population is aging,elderly individuals are increasingly facing significant health challenges,especially mental health issues such as emotional problems,sleep disturbance,and cognitive impairment.Probiotics,defined as live microorganisms that confer health benefits upon the host,have emerged as an effective means to improve the mental health of the elderly.Studies have shown that the gut microbiota regulates brain development and behavior in older adults through the gut-brain axis.This article focuses on summarizing the characteristics of the nervous system in the elderly and its connection to the gut microbiota,the characteristics of the gut microbiota in older individuals,and the mechanisms underlying the regulation of the nervous system in the elderly by the gut-brain axis.It also discusses recent advancements in understanding the role of probiotics in improving mental health conditions of the elderly,such as mild cognitive impairment,insomnia,depression,and Alzheimer's disease,with the aim of providing a theoretical basis for the clinical application of probiotics and the management of mental health in older adults.关键词
肠-脑轴/老年人/精神疾病/益生菌/研究进展Key words
gut-brain axis/older adults/mental disorders/probiotics/research progress分类
轻工业引用本文复制引用
薄志航,王鑫宇,杨振宇,张国芳,杜鹏,李春,刘丽波..益生菌在改善老年人精神健康中的研究进展[J].食品科学,2025,46(6):392-401,10.基金项目
国家乳业技术创新中心课题(2022-科研攻关-9 （）
2024-JSGG-011) （）
呼和浩特市引进高层次创新创业人才(团队)项目(2023RC-高层次-3) （团队）
中央引导地方科技发展资金项目(贵科中引专项2023-3) （贵科中引专项2023-3）
黑龙江省高校协同创新成果项目(LJGXCG2023-048) （LJGXCG2023-048）
