食品与机械2025，Vol.41Issue(2)：121-127,7.DOI:10.13652/j.spjx.1003.5788.2024.60137
阿胶粉缓解体力疲劳的功能评价与机制探讨
Function evaluation and mechanism of Ejiao powder in relieving physical fatigue
韩香 1郭晓飞 2陆晓东 1陈雪梅 3胡博 3王周平1
作者信息
- 1. 江南大学食品学院,江苏 无锡 214122||江南大学国家功能食品工程技术研究中心,江苏 无锡 214122
- 2. 国家胶类中药工程技术研究中心,山东 聊城 252200||聊城市功能性食品研究开发重点实验室,山东 聊城 252200
- 3. 江南大学国家功能食品工程技术研究中心,江苏 无锡 214122
- 折叠
摘要
Abstract
[Objective]To investigate the active mechanism of Ejiao powder,prepared from donkey-hide gelatin,rock sugar,and rice wine,in alleviating physical fatigue in mice.[Methods]Fifty specific pathogen-free(SPF)male BALB/c mice were randomly divided into five groups(10 in each group):a blank negative control group,a model positive control group,and three experimental groups receiving low(0.67 g/kg),medium(1.33 g/kg),and high(2.67 g/kg)doses of Ejiao powder.Except for the control group,all other groups were administered different doses of Ejiao powder via gavage for 30 consecutive days.Following administration,weight-bearing swimming time was recorded,and post-exercise serum urea,muscle glycogen,blood lactic acid,and ATP levels were measured.Additionally,the microbial community in fecal samples was analyzed through genome sequencing.[Results]Compared with the model control group,the low-dose Ejiao powder group exhibited a significant increase in weight-bearing swimming time(P<0.05).Serum urea levels after exercise were significantly reduced in all Ejiao-treated groups(P<0.01),while muscle glycogen reserves in the medium-and high-dose groups showed significant differences(P<0.01).Blood lactic acid levels were significantly decreased(P<0.01),and ATP metabolism was significantly enhanced in the medium-and high-dose groups(P<0.01).Genome sequencing of fecal microbiota revealed a ranking of microbial diversity as follows:medium-dose group>low-dose group>high-dose group>blank control group.Mice in the low-and high-dose Ejiao powder groups exhibited a reduction in Bacteroidetes,while those in the medium-dose group showed a significant increase in Firmicutes,which corresponded to improved carbohydrate and lipid metabolism,providing more energy to alleviate physical fatigue.[Conclusion]Ejiao powder demonstrated an active effect in alleviating physical fatigue in mice and improved microecological imbalance.关键词
阿胶粉/抗疲劳/功效/评价/肠道菌群/基因组Key words
Ejiao powder/anti-fatigue/efficacy/evaluate/intestinal flora/genome引用本文复制引用
韩香,郭晓飞,陆晓东,陈雪梅,胡博,王周平..阿胶粉缓解体力疲劳的功能评价与机制探讨[J].食品与机械,2025,41(2):121-127,7.
