食品科学2025，Vol.46Issue(9)：148-155,8.DOI:10.7506/spkx1002-6630-20241031-211
植物乳植杆菌-30产胞外多糖的结构表征及降尿酸作用
Structural Characterization and Anti-hyperuricemic Activity of Exopolysaccharides Secreted by Lactiplantibacillus plantarum-30
摘要
Abstract
This study obtained a strain producing high yield of exopolysaccharide(EPS),which was identified as Lactiplantibacillus plantarum HZB-30.The strain produced 230.66 mg/L of EPS after fermentation for 28 h.The molecular mass of EPS produced by HZB-30 was 14 639 Da,which was composed of several monosaccharides,such as glucose(37.76％)and galactose(19.15％).The EPS had high inhibitory activity against xanthine oxidase(XO)with an inhibition rate of 80.2％.After in vitro simulated digestion,the digestibility of the EPS was 20.7％,and 43.3％of the initial xanthine oxidase inhibitory activity remained.In an HK-2 cell model of hyperuricemia,the EPS at 20-60 μg/mL effectively decreased the levels of tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β),IL-6,and IL-8 and inhibited the accumulation of uric acid.The findings from this study are both theoretically and practically important for the application of HZB-30-derived EPS to develop anti-hyperuricemic food products.关键词
植物乳植杆菌/胞外多糖/结构表征/降尿酸作用Key words
Lactiplantibacillus plantarum/exopolysaccharides/structural characterization/anti-hyperuricemic activity分类
轻工纺织引用本文复制引用
韩冬,张佳辉,江正强,常畅..植物乳植杆菌-30产胞外多糖的结构表征及降尿酸作用[J].食品科学,2025,46(9):148-155,8.基金项目
"十四五"国家重点研发计划重点专项(2022YFD2101403) （2022YFD2101403）
