食品工业科技2025，Vol.46Issue(9)：456-465,10.DOI:10.13386/j.issn1002-0306.2024060066
植物多酚对线粒体的保护作用研究进展
Research Progress on Mitochondrial Protective Effects of Plant Polyphenols
摘要
Abstract
Plant polyphenols are a class of natural phenolic compounds widely found in nature,known for their significant biological activities such as antioxidant,anti-inflammatory,anti-tumor and cardiovascular and cerebrovascular protective effects.Mitochondria are the energy factories of cells,and their dysfunctions are closely related to human metabolic abnormalities and the development of diseases.In recent years,the role of plant polyphenols in protecting mitochondrial function has received widespread attention.This review summarizes the classification and sources of plant polyphenols,and focuses on their mitochondrial protective effects,which include regulating the levels of mitochondrial reactive oxygen species as well as calcium ions,increasing the activity of mitochondrial respiratory chain enzymes,and regulating mitochondrial fission,fusion and autophagy.These properties with the potential roles contribute to treat diabetes mellitus,lung diseases,fatty liver disease,cardiovascular diseases,and neurodegenerative diseases associated with mitochondrial dysfunction.By summarizing the protective effects of polyphenols on mitochondria,this review will be beneficial for researchers to explore the conformational relationship between polyphenols and the regulation of mitochondrial function and to analyze the molecular mechanisms involved.The review not only provides a scientific basis for the development of novel plant-derived functional ingredients,but also provides a new perspective for dietary intervention on human diseases.关键词
植物多酚/线粒体/功能障碍/疾病/保护作用机制Key words
plant polyphenols/mitochondria/dysfunction/diseases/mechanisms of protective effect分类
轻工纺织引用本文复制引用
刘雨欣,贾茹,吴安楠,李全宏,廖小军,赵婧..植物多酚对线粒体的保护作用研究进展[J].食品工业科技,2025,46(9):456-465,10.基金项目
国家自然科学基金青年科学基金项目(32101977) （32101977）
国家自然科学基金面上项目(32272237) （32272237）
拼多多-中国农业大学研究基金(1061-2424002). （1061-2424002）
