中国食品添加剂2025，Vol.36Issue(5)：158-165,8.DOI:10.19804/j.issn1006-2513.2025.5.021
ACE抑制肽研究进展与组学技术的融合应用
Research progress on ACE inhibitory peptides and integrated application of omics technology
摘要
Abstract
Hypertension has become a significant threat to human health,profoundly impacting cardiovascular health among residents in China.Food-derived angiotensin converting enzyme(ACE)inhibitory peptides have emerged as a promising avenue for hypertension prevention and treatment.These peptides offer advantages such as safety,high activity,easy digestion and good absorption.The rapid development of peptideomics,metabolomics and proteomics technologies have accelerated the ongoing discovery of ACE inhibitory peptides and their mechanisms of action,providing a pathway for quality enhancement and upgrade in related industries.This paper reviewed the current understanding of ACE inhibitory peptides,their action mechanism,activity evaluation,structure-efficacy relationship and industrial application.Furthermore,it explored the integrated application of related omics techniques.This paper aims to provide theoretical guidance for future scientific research and industrial development of ACE inhibitory peptides.关键词
ACE抑制肽/作用机制/活性评价/构效分析/组学/产业应用Key words
angiotensin converting enzyme inhibitory peptide/action mechanism/activity evaluation/structural-activity relationship/omics/industrial applications分类
轻工纺织引用本文复制引用
徐巨才,岑幸仪,刘磊,赵甜甜,郭素琴..ACE抑制肽研究进展与组学技术的融合应用[J].中国食品添加剂,2025,36(5):158-165,8.基金项目
广东省科技创新战略专项市县科技创新支撑(大专项+任务清单)项目(暨2023年江门市关键核心技术"揭榜挂帅"制项目,2023780200060009632) （大专项+任务清单）
广东省基础与应用基础研究基金联合基金项目(2022A1515110711) （2022A1515110711）
五邑大学"创新创业基金"(2023111500000432) （2023111500000432）
