食品与发酵工业2025，Vol.51Issue(10)：198-205,中插6-中插7,10.DOI:10.13995/j.cnki.11-1802/ts.039847
一款低GI乳基代餐粉的研制及其控糖效果研究
Development of meal replacement powder based on dairy with low glycemic index and its hypoglycemic ability in vivo
摘要
Abstract
This study aimed to develop a healthy food product that meets the dietary requirements of type 2 diabetes,aiming to de-crease blood glucose levels and mitigate associated complications.According to the"Dietary Guidelines for Chinese Residents 2022","Guidelines for Medical Nutritional Therapy of Diabetes Mellitus in China 2022",and other documents,a healthy food,meal replacement powder,that can meet the nutritional needs of type 2 diabetes patients was prepared by reasonably adjusting the proportion of dietary nutri-ents and adding a variety of food raw materials with low-glycemic index(GI)and raw materials with homology of medicine and food.The main nutrient content of the product was tested according to the methods specified in the national standard.A high-fat diet combined with streptozotocin induction was used to establish a mouse model of type 2 diabetes to confirm the beneficial effects of meal replacement powder on diabetes.The meal replacement powder formula was based on skimmed milk powder as the main ingredient and added a variety of raw materials with a homology of medicine and food(yam powder,Pueraria Mirifica powder,coix seed powder,and mulberry leaf powder).In animal experiments,meal replacement powder could improve the symptoms of polydipsia and weight loss in mice with type 2 diabetes.In the meal replacement group,fasting blood glucose was decreased,blood glucose tolerance was enhanced,insulin resistance was de-creased,and high-density lipoprotein cholesterol(HDL-C)was increased.Meal replacement powder also decreased alanine aminotrans-ferase(ALT)and aspartate aminotransferase(AST)levels in type 2 diabetic mice,while triglyceride(TG),total cholesterol(TC),and low-density lipoprotein cholesterol(LDL-C)levels were reduced.Moreover,the pathological changes of the liver,kidney,and islet in type 2 diabetic mice were improved in the meal replacement powder group.By referring to the actual nutritional requirements of diabetes patients and various related standards,a healthy food with balanced nutrition and the capacity to control blood sugar was produced.关键词
2型糖尿病/代餐粉/药食同源/降血糖Key words
type 2 diabetes/meal replacement powder/homology of medicine and food/hypoglycemic引用本文复制引用
宋福香,蒲婷,龚志清,凌思婷,章志红,潘瑶,李静,陈芳,邓泽元..一款低GI乳基代餐粉的研制及其控糖效果研究[J].食品与发酵工业,2025,51(10):198-205,中插6-中插7,10.基金项目
江西省中央引导地方科技发展资金项目(20221ZDD02001) （20221ZDD02001）
