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类器官技术在保健食品领域的应用研究进展

张绍时 赵建 郭豫 闫文杰

食品科学2025,Vol.46Issue(14):357-365,9.
食品科学2025,Vol.46Issue(14):357-365,9.DOI:10.7506/spkx1002-6630-20241010-047

类器官技术在保健食品领域的应用研究进展

Recent Progress in the Application of Organoid Technology in the Field of Health Foods

张绍时 1赵建 1郭豫 1闫文杰1

作者信息

  • 1. 北京联合大学生物化学工程学院,生物活性物质与功能食品北京市重点实验室,北京 100023||北京联合大学应用文理学院,保健食品功能检测中心,北京 100191
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摘要

Abstract

With the continuous improvement of the evaluation system for health food technology,the existing evaluation methods are no longer able to meet the needs of future development.Therefore,it is particularly important to develop a more comprehensive and accurate evaluation system that combines advanced technological means with traditional evaluation models.Organoid technology,as a new biological means,can simulate the structure and function of human organs more realistically,improve the accuracy and reliability of experiments,and reduce the need for animal experiments.This paper explores the potential application of 3D organoid technology in health food research from the perspectives of toxicological evaluation,the absorption and metabolism of functional factors,the research and development of health foods for special populations,and the development of new evaluation models for functionalities.It also puts forward new considerations on the development direction of health food evaluation system.The aim is to provide a more accurate and physiologically relevant technical platform for the evaluation system of health foods,so as to promote the scientific research and development and strict supervision of health foods.

关键词

类器官/保健食品/细胞模型/动物模型

Key words

organoids/health foods/cell models/animal models

分类

轻工业

引用本文复制引用

张绍时,赵建,郭豫,闫文杰..类器官技术在保健食品领域的应用研究进展[J].食品科学,2025,46(14):357-365,9.

基金项目

"十四五"国家重点研发计划重点专项(2023YFF1103802) (2023YFF1103802)

食品科学

OA北大核心

1002-6630

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