食品与机械2025，Vol.41Issue(5)：1-9,9.DOI:10.13652/j.spjx.1003.5788.2025.80171
日常饮食中六溴环十二烷的污染情况及潜在健康风险
Status of persistent organic pollutant of brominated flame retardant HBCD in daily diet and its potential health risks
摘要
Abstract
Hexabromocyclododecane(HBCD)is a brominated flame retardant widely used in flame retardant for various industrial and consumer products.Due to its high biotoxicity,bioaccumulation,pollution persistence,and long-range transport capacity,HBCD has been included in the Stockholm Convention list of persistent organic pollutants(POPs)and is being phased out globally.In this paper,the contamination of HBCD,additive brominated flame retardants,in daily diet and the characteristics of HBCD absorption and metabolism in the body are briefly described.Then,the evaluation of HBCD exposure toxicity by bioinformatics,in vitro primary cell models,and cell line models are reviewed.Subsequently,the effects of HBCD intervention on the toxicology of zebrafish models,mouse models,and rat models in vivo are compared.Finally,the total dietary exposure and breast milk exposure in the HBCD population are analyzed.关键词
六溴环十二烷/饮食暴露/吸收代谢/动物模型/健康风险Key words
hexabromocyclododecane/dietary exposure/absorption and metabolism/animal model/health risk引用本文复制引用
赵子瑞,姬海南,赵潺,沈国林,张梦玲..日常饮食中六溴环十二烷的污染情况及潜在健康风险[J].食品与机械,2025,41(5):1-9,9.基金项目
中国质量检验检测科学研究院基本科研业务费项目(编号:2024JK006) （编号:2024JK006）
