中国食品添加剂2025，Vol.36Issue(6)：103-110,8.DOI:10.19804/j.issn1006-2513.2025.6.014
肉桂铬胶囊稳定性及其辅助降血糖作用的人体试食研究
The stability analysis of cinnamon-chromium capsules and their hypoglycemic effects in human trial study
杨彩玲 1杨溢 2张朋朋 1王楠 1李荣 3张红波 3田世民4
作者信息
- 1. 中检科(北京)测试技术有限公司,北京 100176
- 2. 康奥科技集团有限公司,天津 300011
- 3. 江苏艾兰得营养品有限公司,泰州 214500
- 4. 中检科(北京)测试技术有限公司,北京 100176||中国检验检疫科学研究院,北京 100176
- 折叠
摘要
Abstract
In order to investigate the stability of characteristic/effective components in cinnamon-chromium capsules,and to evaluate their adjunctive hypoglycemic effects,accelerated destructive tests were conducted to determine the content of cinnamaldehyde and chromium in cinnamic chromium capsules stored for 0,1,2 and 3 months.A total of 112 participants with type 2 diabetes and impaired glucose regulation were randomly divided into a test group and a control group based on their glycosylated hemoglobin and blood glucose levels.The test group took cinnamon chromium capsule while the control group took an equivalent dose of placebo for 60 days.Subjects' blood glucose changes and the improvement of symptoms were observed.The results indicated that the cinnamon chromium capsule had good stability as the content of cinnamaldehyde and chromium had no significant changes.After taking cinnamon chromium capsule,the main clinical symptoms of test group were significantly improved,and the fasting blood glucose,2 h postprandial blood glucose,glycosylated hemoglobin levels were significantly decreased,while the blood lipid level had no significant increase.No adverse reactions and allergic symptoms were observed during trials.Therefore,it could be concluded that the contents of cinnamaldehyde and chromium in cinnamic-chromium capsule were stable and controllable,then can be used as the index of product quality control in the study of efficacy;The cinnamon-chromium capsule has an auxiliary hypoglycemic effect,and no adverse effect on human health..关键词
肉桂/铬/稳定性/降血糖作用/人体试食Key words
cinnamon/chromium/stability/hypoglycemic effect/human trial分类
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杨彩玲,杨溢,张朋朋,王楠,李荣,张红波,田世民..肉桂铬胶囊稳定性及其辅助降血糖作用的人体试食研究[J].中国食品添加剂,2025,36(6):103-110,8.
