食品工业科技2025，Vol.46Issue(13)：243-250,8.DOI:10.13386/j.issn1002-0306.2024080162
枸杞根黄酮提取工艺优化及其体外抗氧化、降血糖活性
Extraction Process Optimization of Flavonoids from Lycium barbarum Root and Its Antioxidant and Hypoglycemic Activities in Vitro
摘要
Abstract
To investigate the extraction process of flavonoids from Lycium barbarum roots,this study utilized Lycium barbarum roots as the source material and employed an orthogonal experimental design.The optimization of the ethanol extraction method for Lycium barbarum root flavonoids was based on the total flavonoid content.The study also explored the in vitro antioxidant and blood glucose-lowering activities of the Lycium barbarum root extract.The results indicated that the optimal extraction process for Lycium barbarum root flavonoids included a water bath temperature of 60 ℃,an ethanol concentration of 80％,the addition of 0.75％cellulase,and a water bath duration of 90 min.At these conditions,the Lycium barbarum root extract produced the maximum total flavonoid content,reaching 103.61±0.08 mg/g.The Lycium barbarum root extract demonstrated IC50 values of 0.09 mg/mL and 1.06 mg/mL for scavenging DPPH and ABTS+free radicals,respectively.Additionally,the IC50 values for inhibiting α-amylase and α-glucosidase were 7.27 mg/mL and 19.35 mg/mL,respectively,providing impressive in vitro antioxidant and blood glucose-lowering activities.关键词
枸杞根/黄酮/提取/纤维素酶/抗氧化活性/降血糖活性Key words
Lycium barbarum root/flavonoids/extraction/cellulase/antioxidant activity/hypoglycemic activity分类
轻工纺织引用本文复制引用
魏佳仪,禄璐,张渌淘,金波,宁豪奇,李艳萍,米佳,闫亚美..枸杞根黄酮提取工艺优化及其体外抗氧化、降血糖活性[J].食品工业科技,2025,46(13):243-250,8.基金项目
宁夏重点研发项目(2021BEF02008) （2021BEF02008）
宁夏"枸杞功效物质基础研究与深加工产品研发"科技创新团队项目(2024CXTDOO7). （2024CXTDOO7）
