食品工业科技2025，Vol.46Issue(13)：441-452,12.DOI:10.13386/j.issn1002-0306.2024070432
乳源外泌体的内外源效应及其调节肠道健康研究进展
Advances in the Endogenous and Exogenous Effects of Milk-derived Exosomes and Regulation of Intestinal Health
庞洋 1李懿 1栾悦 2王腾 1王勤 2贺晓云1
作者信息
- 1. 中国农业大学食品科学与营养工程学院,北京 100083
- 2. 中国农业大学动物科学技术学院,北京 100083
- 折叠
摘要
Abstract
Milk and dairy products serve as crucial sources of nutrition for humans,and their composition is extensively researched.Milk exosomes are nanoscale phospholipid bilayer vesicles released from the milk source and present in the extracellular environment,which contain protein,lipid,and genetic material,among other cell-specific substances.Milk exosomes distinguish themselves from other types of exosomes in that they are rich in sources and readily producible on a large scale.They can be selectively absorbed by target cells to exert physiological effects and thereby influence various physiological and pathological processes.Milk exosomes directly participate in and regulate diverse physiological processes by carrying their endogenous bioactive molecules including proteins,microRNAs,and lipids,manifesting significant biological activity,likewise act as ideal carriers of active substances due to their outstanding biocompatibility and high loading capacity,rendering them suitable for drug delivery and transportation.Hence,this article summarizes the effects of endogenous active substances and the role of milk exosomes as signal transduction carriers,and reviews the latest research progress in regulating intestinal health,so as to facilitate in-depth research and extensive application of milk exosomes in domains such as food science,nutrition,and medicine.关键词
乳源外泌体/microRNAs/载体效应/肠道健康/生理学功能Key words
milk-derived exosomes/microRNAs/carrier effect/gut health/physiological function分类
轻工纺织引用本文复制引用
庞洋,李懿,栾悦,王腾,王勤,贺晓云..乳源外泌体的内外源效应及其调节肠道健康研究进展[J].食品工业科技,2025,46(13):441-452,12.
