CT理论与应用研究2025，Vol.34Issue(4)：598-603,6.DOI:10.15953/j.ctta.2024.305
肺间质性疾病CT严重度分级及与肺功能的相关性研究
The Correlation between Computed Tomography Severity Grade and Pulmonary Function in Interstitial Lung Disease
摘要
Abstract
Objective:To assess whether there is a correlation between CT scan severity score and pulmonary function in Interstitial Lung Disease,and provide a more reliable basis for clinical diagnosis and treatment.Materials and Methods:Sixty patients with clinical diagnosis of Interstitial Lung Disease(ILD)were collected,and chest CT and pulmonary function tests were performed at the same time.Here DLCO%and FEV1%were used as the pulmonary function indexes.The severity of the patients was assessed by CT scores as mild(range,1～10),moderate(range 11～20),and severe(range 21～30).Correlation analysis was carried out between CT score and pulmonary function index,and the lung function parameters of patients at three grades were compared between groups and pairwise among the means.Results:As per the CT severity classification,there were 13 mild cases,31 moderate cases,and 16 severe cases.CT score was negatively correlated with DLCO%and FEV1%.R value was-0.814 and-0.797,respectively;The comparison of the mean value of DLCO%and FEV1%among the three groups and the pairings of the mean value of DLCO%and FEV1%were statistically significant.Conclusion:There was good correlation between CT score of ILD and the pulmonary function index.The pulmonary function index of patients with different CT severity grading was statistically significant,which can provide a new basis for the clinical evaluation and diagnosis of the disease.关键词
肺疾病/间质性/CT/分级/肺功能Key words
lung disease/interstitial/CT/severity grade/pulmonary function分类
医药卫生引用本文复制引用
高慧,刘勇彬,肖旻,张静,刘琴..肺间质性疾病CT严重度分级及与肺功能的相关性研究[J].CT理论与应用研究,2025,34(4):598-603,6.基金项目
Funding was providing by the Shenzhen City Nanshan District Science and Technology Plan Project(Medical and Health Category)(Grant No.2018073). （Medical and Health Category）
