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乳蛋白肽的制备及其生物活性研究进展

薄志航 韦家周 苏权 李春梅 刘丽波 张国芳 李春 陈志成

乳业科学与技术2025,Vol.48Issue(4):45-53,9.
乳业科学与技术2025,Vol.48Issue(4):45-53,9.DOI:10.7506/rykxyjs1671-5187-20250228-013

乳蛋白肽的制备及其生物活性研究进展

Research Progress on the Preparation and Biological Activities of Milk Protein-Derived Peptides

薄志航 1韦家周 2苏权 2李春梅 3刘丽波 4张国芳 4李春 4陈志成2

作者信息

  • 1. 东北农业大学食品学院,乳品科学教育部重点实验室,黑龙江 哈尔滨 150030
  • 2. 广西农垦西江乳业有限公司,广西 贵港 537104
  • 3. 广西职业技术学院,广西 南宁 530226
  • 4. 东北农业大学食品学院,乳品科学教育部重点实验室,黑龙江 哈尔滨 150030||黑龙江省绿色食品科学研究院,黑龙江 哈尔滨 150028
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摘要

Abstract

As an important functional protein resource in dairy products,milk protein has become a research hotspot due to its excellent nutritional value and multiple biological activities.Recent studies have made breakthrough progress in the preparation and functional analysis of milk protein-derived peptides.There are various bio-processing methods to precisely release bioactive peptides with specific functions from milk protein,such as directed enzymatic hydrolysis and controlled fermentation.These active components demonstrate significant health benefits in antioxidant defense,pathogen inhibition,immune homeostasis regulation,and blood pressure control.This paper systematically reviews the technologies for the preparation of milk protein-derived peptides,including enzymatic hydrolysis,microbial fermentation,chemical synthesis and computer simulation and prediction techniques,and conducts a comparative analysis the effectiveness and characteristics of these technologies.Furthermore,it elucidates the mechanisms by which milk protein-derived peptides exert their biological activities and their bioavailability,and evaluates their potential for application in functional foods and pharmaceutical formulations.By integrating existing research findings,this review provides a scientific basis for optimizing the production process of milk protein-derived peptides and expanding their application scenarios,thereby promoting their industrial development.

关键词

乳蛋白/乳蛋白肽/制备技术/酶解/生物活性/产业化应用

Key words

milk protein/milk protein-derived peptides/preparation technology/enzymatic hydrolysis/biological activity/industrial application

分类

轻工纺织

引用本文复制引用

薄志航,韦家周,苏权,李春梅,刘丽波,张国芳,李春,陈志成..乳蛋白肽的制备及其生物活性研究进展[J].乳业科学与技术,2025,48(4):45-53,9.

基金项目

中央引导地方科技发展专项资金(区域创新体系建设类)项目(贵科中引专项2023-3) (区域创新体系建设类)

外国专家重点支撑项目(东北专项)(D20240070) (东北专项)

乳业科学与技术

1671-5187

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