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抗冻肽低温保存机制及应用

王依真 夏永军 熊智强 艾连中 王光强

食品与发酵工业2025,Vol.51Issue(17):379-384,6.
食品与发酵工业2025,Vol.51Issue(17):379-384,6.DOI:10.13995/j.cnki.11-1802/ts.041877

抗冻肽低温保存机制及应用

Cryopreservation mechanisms and applications of antifreeze peptides

王依真 1夏永军 1熊智强 1艾连中 1王光强1

作者信息

  • 1. 上海理工大学健康科学与工程学院,上海,200093
  • 折叠

摘要

Abstract

Antifreeze peptides are a class of small proteins that possess the unique ability to inhibit ice crystal growth and lower the freezing point of solutions without affecting the melting point.These peptides attract significant attention for their potential in cryopreserva-tion,providing a novel approach to preserving biological materials at low temperatures.Current review provides an in-depth analysis of the mechanisms by which antifreeze peptides exert their cryoprotective effects,detailing their structural features and the underlying physics that enable them to interact with ice crystals.It also evaluates their applications in cry opreservation,emphasizing their role in maintaining cell viability and integrity during the freezing and thawing processes.The review highlights the significance of peptides in advancing cryobi-ology and their potential impact on industrial and medical cryopreservation practices.This concise yet comprehensive summary offers a clear understanding of the current state of research on antifreeze peptides and their future trajectory in the field of low-temperature biology and biotechnology.

关键词

抗冻肽/低温保护剂/作用机制/应用

Key words

antifreeze peptides/cryoprotectant/mechanism/application

引用本文复制引用

王依真,夏永军,熊智强,艾连中,王光强..抗冻肽低温保存机制及应用[J].食品与发酵工业,2025,51(17):379-384,6.

基金项目

国家自然科学基金面上项目(32172186) (32172186)

济南市"新高校20条"资助项目(2021GXRC057) (2021GXRC057)

无锡市产业创新研究院先导技术预研项目(XD23001) (XD23001)

食品与发酵工业

OA北大核心

0253-990X

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