中国食品添加剂2025，Vol.36Issue(9)：51-57,7.DOI:10.19804/j.issn1006-2513.2025.9.007
阿尔泰金莲花总黄酮提取工艺优化及其抗氧化与抗菌活性研究
Optimization extraction of total flavonoids from Trollius altaicus and their antioxidant and antibacterial activities
摘要
Abstract
In order to optimize the extraction of total flavonoids from Trollius altaicus and explore its antioxidant and antibacterial activities.Orthogonal experiments combined with a Backpropagation(BP)neural network was used to optimize the extraction process of total flavonoids from Trollius altaicus,using total flavonoids yield as the primary indicator.The antioxidant activity of total flavonoids from Trollius altaicus was evaluated by their scavenge ability of ABTS and DPPH free radicals,as well as their total reducing power.The antibacterial activity was evaluated against Streptococcus mutans and assessed using the agar well diffusion method.Results showed that the optimal extraction process for total flavonoids from Trollius altaicus were a solid-liquid ratio of 1∶20,three extraction cycles and an extraction time of 100 minutes.Under these conditions,the total flavonoids extraction rate was 7.72%.The flavonoid extract demonstrated good free radical scavenging ability and inhibitory effects on streptococcus mutans.In conclusion,the established BP neural network model effectively predicted the optimal conditions for flavonoid extraction.The total flavonoids from Trollius altaicus possessed notable antioxidant and antibacterial activities,suggesting their potential for further development.关键词
阿尔泰金莲花/总黄酮/BP神经网络/抗氧化活性/抗菌活性Key words
Trollius altaicus/total flavonoids/BP neural network/antioxidant activity/antibacterial activity分类
轻工纺织引用本文复制引用
姜敏,李金晶,祖丽皮艳·阿布力米特,丁茂鹏..阿尔泰金莲花总黄酮提取工艺优化及其抗氧化与抗菌活性研究[J].中国食品添加剂,2025,36(9):51-57,7.基金项目
新疆维吾尔自治区青年科学基金(项目名称:阿尔泰金莲花总黄酮提取工艺优化及其抗菌活性成分的鉴定与作用机理研究项目编号:2022D01B155) （项目名称:阿尔泰金莲花总黄酮提取工艺优化及其抗菌活性成分的鉴定与作用机理研究项目编号:2022D01B155）
新疆第二医学院大学生创新创业训练计划项目(项目编号:202313560007) （项目编号:202313560007）
