CT理论与应用研究2025，Vol.34Issue(6)：1068-1081,14.DOI:10.15953/j.ctta.2025.366
时空混合能谱调制锥束CT成像中的调制器设计
Modulator Design for Spectral Cone-beam CT Using Spatial-temporal Mixed Spectral Modulation
摘要
Abstract
Flat-panel detector-based cone-beam computed tomography(CBCT)has demonstrated significant potential for applications in medical diagnostics and non-destructive testing.However,the coupling of stronger scatter artifacts and beam hardening effects in CBCT has long limited its quantitative imaging performance.Recently,a novel CBCT imaging technique called"spatial-temporal mixed spectral modulation"has been proposed.It can generate multi-energy spectral data with similar scattering distribution and good alignment of spectral projections,and it has the potential for multi-energy imaging with simultaneously scattering correction capability.This article presents an optimized design of the spectral modulator,which serves as the key hardware for the proposed imaging technique.We first determined the pattern of the spectral modulator based on its physics model and manufacturing difficulty.Subsequently,we selected the material,thickness,and period according to the analysis of the spectral imaging performance and the validation of scatter similarity hypothesis.Finally,we fabricated an overlapped spectral modulator with thicknesses of(0.2+0.4)mm Mo.Physical experiments demonstrated that this modulator can achieve enhanced CBCT quantitative imaging performance using the corresponding spectral-scatter decoupling algorithm.关键词
时空混合能谱调制/能谱调制器/锥束CT/散射校正/能谱成像Key words
Spatial-temporal mixed spectral modulation/spectral modulator/cone-beam CT/scatter correction/spectral imaging分类
能源科技引用本文复制引用
邓一凡,高河伟..时空混合能谱调制锥束CT成像中的调制器设计[J].CT理论与应用研究,2025,34(6):1068-1081,14.基金项目
国家重点研发计划(面向介入诊疗精准脑成像的C型臂能谱CT关键技术创新(2022YFE0131100)) （面向介入诊疗精准脑成像的C型臂能谱CT关键技术创新(2022YFE0131100）
国家自然科学基金(基于时空混合能谱调制的新型锥束CT定量成像物理和关键技术研究(12075130)). （基于时空混合能谱调制的新型锥束CT定量成像物理和关键技术研究(12075130）
