食品与发酵工业2025，Vol.51Issue(24)：397-408,12.DOI:10.13995/j.cnki.11-1802/ts.042907
基于纳米抗体的食源性致病菌快速检测方法研究进展
Research progress of nanobody-based rapid detection methods for foodborne pathogens
摘要
Abstract
Foodborne pathogens pose a severe threat to the field of food safety and exert extremely adverse effects on human life and health.With the rapid development of the food industry and the continuous improvement of rapid food detection technologies,immunoas-says for foodborne pathogens have become a hot topic in the field of food rapid detection.Nanobodies,as the smallest type of antibodies ca-pable of specific binding to antigens,exhibit numerous advantages compared to conventional antibodies,including strong affinity,high sensitivity,good stability,and ease of large-scale production.They have been widely applied in the detection of various foodborne hazards,demonstrating immense potential in the field of food safety.This article introduces the structures and physicochemical properties of nano-bodies,reviews the latest research progress in the rapid detection of foodborne pathogenic bacteria using nanobodies,and finally summari-zes the characteristics of different innovative technologies in this field.The aim is to provide theoretical support and practical guidance for the application of nanobodies in rapid detection of foodborne pathogen.关键词
纳米抗体/食源性致病菌/快速检测技术/食品安全Key words
nanobody/foodborne pathogen/rapid detection technology/food safety引用本文复制引用
张家豪,包雨宁,王妍入..基于纳米抗体的食源性致病菌快速检测方法研究进展[J].食品与发酵工业,2025,51(24):397-408,12.基金项目
国家自然科学基金面上项目(32472439) （32472439）
大学生创新创业项目(X202410712573) （X202410712573）
