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益生元调节老年肠道微生态及代谢的机制研究进展

LIU Wenjun WANG Pan WANG Yubin WANG Dan ZHAO Wenting ZHAO Yuanyuan ZHAO Xiaoyan ZHANG Chunhong

食品工业科技2026,Vol.47Issue(2):448-459,12.
食品工业科技2026,Vol.47Issue(2):448-459,12.DOI:10.13386/j.issn1002-0306.2025010138

益生元调节老年肠道微生态及代谢的机制研究进展

Research Progress on the Mechanism of Prebiotics Regulating Intestinal Microecological and Metabolism in the Elderly

LIU Wenjun 1WANG Pan 2WANG Yubin 2WANG Dan 2ZHAO Wenting 2ZHAO Yuanyuan 2ZHAO Xiaoyan 1ZHANG Chunhong3

作者信息

  • 1. College of Food Science,Shenyang Agricultural University,Shenyang 110866,Chin||Institute of Agri-food Processing and Nutrition,Beijing Academy of Agriculture and Forestry Sciences,Beijing Key Laboratory of Agricultural Products of Fruits and Vegetables Preservation and Processing,Key Laboratory of Vegetable Postharvest Processing,Ministry of Agriculture and Rural Affairs,Beijing 100097,China
  • 2. Institute of Agri-food Processing and Nutrition,Beijing Academy of Agriculture and Forestry Sciences,Beijing Key Laboratory of Agricultural Products of Fruits and Vegetables Preservation and Processing,Key Laboratory of Vegetable Postharvest Processing,Ministry of Agriculture and Rural Affairs,Beijing 100097,China
  • 3. College of Food Science,Shenyang Agricultural University,Shenyang 110866,Chin
  • 折叠

摘要

Abstract

With the increasing prevalence of global aging,China is confronted with a significant challenge posed by an aging population.The intestinal microecological health of the elderly has emerged as a critical research focus.This paper comprehensively examines the beneficial impacts of prebiotics on intestinal barrier function and immune modulation.These effects are attained through the stimulation of beneficial bacteria growth,the suppression of pathogenic bacteria proliferation,and the augmentation of short-chain fatty acid synthesis.Additionally,the paper summarizes the potential of prebiotics in managing prevalent metabolic disorders in the elderly,including obesity,hyperglycemia,and hyperlipidemia.Moreover,a comparative assessment is carried out on the action features of various prebiotics,such as inulin and fructooligosaccharides.At present,the application mechanisms of prebiotics in the elderly population are not fully comprehended,and their overall effectiveness requires further investigation.Future studies place emphasis on investigating the synergistic actions of prebiotics combined with other dietary or pharmacological interventions and accelerate the development of innovative,highly efficient prebiotic products specifically designed for the elderly,thus enhancing the accuracy and applicability of nutritional intervention approaches.

关键词

益生元/老年肠道微生态/代谢性疾病/菌群结构/菌群代谢物

Key words

prebiotics/intestinal microecology in the elderly/metabolic diseases/microbiota structure/microbiota metabolites

分类

轻工纺织

引用本文复制引用

LIU Wenjun,WANG Pan,WANG Yubin,WANG Dan,ZHAO Wenting,ZHAO Yuanyuan,ZHAO Xiaoyan,ZHANG Chunhong..益生元调节老年肠道微生态及代谢的机制研究进展[J].食品工业科技,2026,47(2):448-459,12.

基金项目

北京市农林科学院优秀青年基金(YXQN202202) (YXQN202202)

北京市农林科学院科技创新能力建设专项(KJCX20240402,KJCX20240507) (KJCX20240402,KJCX20240507)

北京市农林科学院青年英才引进基金(130110114). (130110114)

食品工业科技

1002-0306

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