乳业科学与技术2026，Vol.49Issue(1)：16-22,7.DOI:10.7506/rykxyjs1671-5187-20251020-070
Ligilactobacillus cholophilus BD7642全基因组分析及功能预测
Whole Genome Analysis and Functional Prediction of Ligilactobacillus cholophilus BD7642
摘要
Abstract
A novel strain of Ligilactobacillus cholophilus,designated BD7642,was isolated from pickled potherb mustard(Brassica juncea Coss.)in Shanghai.The complete genome sequence of the strain was obtained using a combination of PacBio and Illumina sequencing.To characterize this strain and explore its potential probiotic functions,we performed comprehensive genomic analyses.The results showed that the genome of L.cholophilus BD7642 was 1 587 935 bp in size and encoded 1 530 genes(no plasmids detected).Functional annotation and secondary metabolite synthesis analysis revealed that L.cholophilus BD7642 contained gene clusters for the biosynthesis of the bacteriocin mutacin 1140 and type III polyketide synthases and possessed a great capacity for environmental adaptation.ResFinder analysis indicated the absence of antibiotic resistance genes.Comparative genomics uncovered the genomic uniqueness of L.cholophilus BD7642.This study provides a deep understanding of L.cholophilus BD7642 and offers a reference for exploiting its probiotic potential.关键词
Ligilactobacillus cholophilus/基因组学/生物信息学/细菌素Key words
Ligilactobacillus cholophilus/genomics/bioinformatics/bacteriocin分类
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任全路..Ligilactobacillus cholophilus BD7642全基因组分析及功能预测[J].乳业科学与技术,2026,49(1):16-22,7.基金项目
上海市国资委企业创新发展和能级提升项目(2022013) （2022013）
"十四五"国家重点研发计划重点专项(2022YFD2100704) （2022YFD2100704）
