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母乳免疫球蛋白含量动态变化及其影响因素研究进展

贾宏信 苏米亚 陈文亮

乳业科学与技术2026,Vol.49Issue(1):62-69,8.
乳业科学与技术2026,Vol.49Issue(1):62-69,8.DOI:10.7506/rykxyjs1671-5187-20250909-059

母乳免疫球蛋白含量动态变化及其影响因素研究进展

A Review on the Dynamic Changes and Influencing Factors of Immunoglobulin Contents in Human Milk

贾宏信 1苏米亚 1陈文亮1

作者信息

  • 1. 乳业生物技术国家重点实验室,上海乳业生物工程技术研究中心,光明乳业股份有限公司乳业研究院,上海 201103
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摘要

Abstract

Human milk provides adequate nutrition for infants'early development and is rich in immunologically active substances,protecting infants against diseases before their own immune systems mature.Secretory immunoglobulin A(sIgA),IgM,and IgG,the major immunologically active substances in human milk,have been most extensively studied.The concentration and composition of Igs in human milk change with the lactation period,which is influenced not only by lactation stages(colostrum,transitional and mature milk)but also by the lactating mother's living environment,dietary nutrition,gestational age,and other factors.This paper systematically reviews the concentrations and influencing factors of Igs in human milk from different countries and regions,with the aim of providing references for the in-depth research and application development of active components in human milk.

关键词

母乳/分泌型免疫球蛋白A/免疫球蛋白G/免疫球蛋白M/影响因素

Key words

human milk/secretory immunoglobulin A/immunoglobulin G/immunoglobulin M/influencing factors

分类

轻工纺织

引用本文复制引用

贾宏信,苏米亚,陈文亮..母乳免疫球蛋白含量动态变化及其影响因素研究进展[J].乳业科学与技术,2026,49(1):62-69,8.

基金项目

上海市国资委企业创新发展和能级提升项目(2022013) (2022013)

乳业科学与技术

1671-5187

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