CT理论与应用研究2026，Vol.35Issue(2)：231-238,8.DOI:10.15953/j.ctta.2025.172
基于光谱CT在低剂量对比剂和流率肺动脉成像中的可行性研究
Feasibility Study of Spectral CT for Pulmonary Angiography Using Low-volume Contrast Agent and Low-flow-rate Protocol
朱思思 1谢孟臻 1漆安琪 1罗佳鑫 2吴斌 1杨忠现 1刘于宝1
作者信息
- 1. 南方医科大学深圳医院医学影像中心,广东 深圳 518110
- 2. 浙江中医药大学第四临床医学院,杭州 310059
- 折叠
摘要
Abstract
Objective:To explore the feasibility of using a low-dose contrast agent volume and a low flow rate in dual-layer detector spectral computed tomography(CT)for CT pulmonary angiography(CTPA).Methods:In total,80 patients clinically diagnosed with pulmonary embolisms were collected for CTPA examination and randomly divided into two groups,comprising 40 cases each.The low-dose group received a contrast agent dose of 15 mL at a flow rate of 2 mL/s,and the images were reconstructed using a 40 keV monochromatic spectrum.The conventional group underwent a small-dose test with a contrast agent dose of 50 mL at a flow rate of 5.0 mL/s.The volume CT dose index(CTDIvol),dose-length product(DLP),effective dose(ED),CT values,signal-to-noise ratio(SNR),and contrast-to-noise ratio(CNR)were recorded and calculated for both groups,and the image quality was subjectively scored.Results:(1)The differences in these indicators between the two groups were statistically significant.The pulmonary artery CT values for the conventional and the low-dose groups were 368.450 HU and 569.050 HU,respectively,with a statistically significant difference between the two groups.There were statistically significant differences in SNR and CNR between the two groups.(2)There was no statistically significant difference in the subjective scoring of image quality between the two groups.(3)The DLP values for the conventional and low-dose groups were 376.500 mGy/cm and 294.500 mGy/cm,respectively;the CTDIvol values were 11.150 mGy and 8.350 mGy,respectively;and the ED values were 5.271 mSv and 4.123 mSv,respectively,with statistically significant differences between the groups.Conclusion:The scanning protocol with the"low"contrast agent dose and flow rate using dual-layer detector spectral CT for CTPA examinations met the diagnostic requirements while reducing risks such as contrast extravasation and contrast-induced nephropathy.关键词
双层探测器光谱CT/肺动脉CTA/低剂量对比剂/单能谱成像Key words
dual-layer detector spectral CT/pulmonary artery CTA/low-dose contrast agent/monochromatic imaging分类
医药卫生引用本文复制引用
朱思思,谢孟臻,漆安琪,罗佳鑫,吴斌,杨忠现,刘于宝..基于光谱CT在低剂量对比剂和流率肺动脉成像中的可行性研究[J].CT理论与应用研究,2026,35(2):231-238,8.
