食品与发酵工业2026，Vol.52Issue(6)：192-201,中插12-中插15,14.DOI:10.13995/j.cnki.11-1802/ts.042963
天麻保健食品组方规律及主要保健功能研究
Research on the formation pattern and main health functions of Gastrodia elata Blume health foods
摘要
Abstract
This study aims to clarify the formulae of health food products containing Gastrodia elata Blume(G.elata)and the mecha-nism of its main health functions.Through the statistics of health food containing G.elata registered in the State Administration for Market Supervision and Administration,the basic information such as the year of approval,dosage form,health function and suitable/contraindi-cated groups were analysed,and frequency statistics and association rule analysis were also carried out.The main mechanisms of health functions exerted by G.elata health food products were also investigated through network pharmacology and molecular docking technology.As a result,a total of 136 health food products containing G.elata were collected,of which the largest number was in capsule form;11 health functions were involved,mainly helping to improve sleep,helping to enhance immunity,and helping to maintain a healthy level of blood pressure;a total of 96 traditional Chinese medicines(TCM)were involved in the composition of raw materials,with warmth and sweetness being the main ones;and 161 active ingredients and 1 037 targets of G.elata were obtained,which exerted their main health effects mainly through signaling pathways such as the interactions of neuroactive ligands and receptors,PI3K-AKT,HIF1 and other signa-ling pathways.Data mining and network pharmacology techniques can predict the formulation mode,health functions and potential action targets and mechanism of action of health food products containing G.elata,and provide a reference basis for the research and development of G.elata-related products.关键词
天麻/保健食品/数据挖掘/网络药理学/改善睡眠/增强免疫力/维持血压健康水平Key words
Gastrodia elata Blume/health product/data mining/network pharmacology/improving sleep/enhancing immunity/main-taining healthy blood pressure levels引用本文复制引用
贾凡凡,康思锐,张骁睿,张博丰,陈琛..天麻保健食品组方规律及主要保健功能研究[J].食品与发酵工业,2026,52(6):192-201,中插12-中插15,14.基金项目
陕西省重点研发项目(2025NC-YBXM-308) （2025NC-YBXM-308）
陕西省教育厅重点科学研究计划项目(23JY017) （23JY017）
陕西理工大学"市校共建"科研专项(SXC-2301) （SXC-2301）
陕西理工大学科研项目(SLGRCQD045) （SLGRCQD045）
陕西理工大学研究生创新基金项目(SLGYCX2527) （SLGYCX2527）
