中国食物与营养2026，Vol.32Issue(3)：72-79,49,9.
岩藻多糖抗幽门螺杆菌感染的效果及应用价值分析
Role of Fucoidan from Seaweeds in Anti-Helicobacter pylori Infection
摘要
Abstract
[Objective]To integrate evidence,clarify fucoidan's anti-Helicobacter pylori(Hp)mechanism,clinical efficacy and safety.[Method]PubMed and other databases were searched for preclinical/clinical studies on fucoidan against Hp(up to July 15,2024).Literature was screened per PRISMA guidelines;evidence was integrated via quality grading and subgroup analysis,focusing on mechanism and clinical potential.[Result]A total of 369 studies were identified,of which 14 met the inclusion criteria.The analysis demonstrated that fucoidan significantly inhibits the adhesion of Hp and effectively protects the gastric mucosa,preventing and cor-recting antibiotic-induced dysbiosis of gut microbiota.[Conclusion]Fucoidan,a natural ingredient,has"colonization inhibition-mucosa protection-gut microbiota regulation"advantages,showing notable potential for adjuvant therapy of Hp infection.关键词
岩藻多糖/幽门螺杆菌/作用机制/临床效果/安全性Key words
fucoidan/Helicobacter pylori/mechanism/clinical efficacy/safety引用本文复制引用
高婷婷,曲晨菲,于云,孔晶晶,姜山..岩藻多糖抗幽门螺杆菌感染的效果及应用价值分析[J].中国食物与营养,2026,32(3):72-79,49,9.基金项目
山东省医药卫生科技发展计划项目(项目编号:202212070309) （项目编号:202212070309）
横向课题(项目编号:KZJSKF2024019). （项目编号:KZJSKF2024019）
