中国食物与营养2026，Vol.32Issue(3)：194-200,184,8.
短期低热量饮食干预中健康成人的血脂波动模式:一项初步研究
Study on the Fluctuation Patterns of Blood Lipids in Healthy Adults During Short-Term Low-Calorie Diet Intervention
摘要
Abstract
[Objective]To investigate the effects of a 14-day strictly controlled low-calorie diet intervention on the dynamic changes in blood lipid profiles of healthy adults.[Method]A total of 25 healthy adult subjects were recruited and underwent a 14-day standardized low-calorie diet intervention.Centralized meal provision and on-site supervision were implemented to ensure compliance.Fasting venous blood was collected at baseline and multiple time points after intervention to measure total cholesterol,triglycerides,high-density lipoprotein cholesterol,and low-density lipoprotein cholesterol levels,and their dynamic changes were analyzed.[Result]In the early intervention phase(days 1-3),total cholesterol,low-density lipoprotein cholesterol,and high-density lipoprotein cholesterol levels transiently increased,while triglycerides decreased significantly.In the mid-to-late intervention phase(days 4-14),total cholesterol,low-density lipoprotein cholesterol,and high-density lipoprotein cholesterol levels all declined significantly,while triglycerides continued to decrease.Body weight decreased significantly,but no statistically significant change was observed in body fat percentage.[Conclusion]Short-term low-calorie diet intervention can induce a biphasic fluctuation pattern in blood lipid profiles of healthy adults,characterized by an initial increase followed by a decrease,suggesting that the assessment of dietary intervention effects should consider the temporal changes in blood lipid parameters.关键词
低热量饮食/血脂/动态变化/双相波动/健康成人Key words
low-calorie diet/blood lipids/dynamic changes/biphasic fluctuation/healthy adults引用本文复制引用
李孜孜,李莹莹,李影,朱铭钰,孙晓玉,范博艺,沈辰谕,苑晓琳,向雪松..短期低热量饮食干预中健康成人的血脂波动模式:一项初步研究[J].中国食物与营养,2026,32(3):194-200,184,8.基金项目
国家重点研发计划重点专项课题(课题编号:2024YFF1105601) （课题编号:2024YFF1105601）
达能营养中心膳食营养研究与宣教基金项目(项目编号:DIC2024-04). （项目编号:DIC2024-04）
