中国食品添加剂2026，Vol.37Issue(4)：98-104,7.DOI:10.19804/j.issn1006-2513.2026.4.012
基于UPLC-Q-Orbitrap高分辨质谱的现制饮料中20种合成着色剂及染料的分析方法
Analytical method for 20 synthetic colorants and dyes in freshly prepared beverages using UPLC-Q-Orbitrap HRMS
摘要
Abstract
A rapid detection system based on UPLC-Q-Orbitrap HRMS for simultaneous analysis of 11 synthetic colorants and 9 dyes in freshly prepared beverages was developed.A simple acetonitrile extraction-water dilution pretreatment was employed,with gradient elution performed on a C18 MG Ⅲ column using 10 mmol/L ammonium acetate aqueous solution and acetonitrile containing 0.05％acetic acid as mobile phases.Detection was carried out in positive/negative ion switching mode via electrospray ionization,and high-accuracy mass data were acquired using full scan/data-dependent MS2(Full MS/dd-MS2)acquisition.Method validation demonstrated excellent linearity(R2＞0.9971)for all the 20 target analytes in the range of 0.0038～0.12 mg/kg,with average spiked recoveries of 72.6％～107.9％and precision RSDs of 2.0％～8.5％.The method was characterized by simplicity,high sensitivity,and reliability,meeting the requirements for high-throughput screening and quantitative detection of synthetic colorants and dyes in freshly prepared beverages.关键词
超高效液相色谱-四极杆/静电场轨道阱高分辨质谱/现制饮料/合成着色剂/染料Key words
ultra-performance liquid chromatography-quadrupole-orbitrap high-resolution mass spectrometry(UPLC-Q-Orbitrap HRMS)/freshly prepared beverages/synthetic colorants/dyes分类
轻工纺织引用本文复制引用
廖浩,农毅清,蒋湘,冯婷..基于UPLC-Q-Orbitrap高分辨质谱的现制饮料中20种合成着色剂及染料的分析方法[J].中国食品添加剂,2026,37(4):98-104,7.基金项目
广西壮族自治区市场监督管理局科技计划项目(GXSJKJ2023-19) （GXSJKJ2023-19）
