食品科学2026，Vol.47Issue(8)：1-18,18.DOI:10.7506/spkx1002-6630-20260115-127
功能性食品蛋白结构调控机理、策略及未来发展趋势
Advances in Structural Modulation of Functional Food Proteins:Mechanisms,Strategies,and Future Trends
摘要
Abstract
Proteins,as core macronutrients in human nutrition,play irreplaceable roles in growth and development,tissue repair,and physiological regulation.With the acceleration of population aging and the rising demand for health-oriented products,functional food proteins have attracted increasing attention for their health benefits beyond basic nutrition,showing broad application prospects in medical foods,sports nutrition,and healthy aging.The functional properties of proteins are highly dependent on their complex hierarchical structures.However,conventional food processing often causes uncontrolled disruption to these structures,thereby limiting their application potential.Therefore,how to achieve targeted regulation of protein structure and function through precise regulation strategies has become an important research issue in food science.This review systematically summarizes the theoretical basis for the structural regulation of food proteins,including denaturation and renaturation mechanisms,intermolecular interactions,and multi-scale characterization methods for conformational changes.It highlights advances in various structural regulation techniques,such as physical field treatments(e.g.,high pressure,ultrasound,and cold plasma),biological approaches(e.g.,enzymatic hydrolysis,fermentation,and genetic engineering),and green chemical methods(e.g.,pH-shifting and glycosylation).The synergistic effects of combined physical and biological approaches are also discussed.Furthermore,this review discusses the potential of functional food proteins in different application scenarios.In light of current challenges and industrial obstacles,it proposes that future research should focus on precise regulation mechanisms,cross-scale structure-function relationships,and the development of sustainable processing technologies.This review provides a comprehensive perspective on the structural modulation and innovative processing of food proteins,aiming to support both scientific research and industrial innovations in functional foods.关键词
食品蛋白/结构调控/创新加工/功能性食品/可持续营养Key words
food proteins/structural modulation/innovative processing/functional foods/sustainable nutrition分类
轻工纺织引用本文复制引用
隋晓楠,曹子辰,李小骞,兰天..功能性食品蛋白结构调控机理、策略及未来发展趋势[J].食品科学,2026,47(8):1-18,18.基金项目
"十四五"国家重点研发计划项目(2024YFF1106500) （2024YFF1106500）
