乳业科学与技术2026，Vol.49Issue(3)：11-16,6.DOI:10.7506/rykxyjs1671-5187-20260220-015
植物乳植杆菌SC-1全基因组测序及安全性评价
Whole Genome Sequencing and Safety Evaluation of Lactiplantibacillus plantarum SC-1
摘要
Abstract
Lactiplantibacillus plantarum SC-1,a strain able to promote the production of ergosterol by Monascus isolated from naturally fermented Chinese sauerkraut,was evaluated for genetic characteristics and application safety.Whole genome sequencing and Kyoto Encyclopedia of Genes and Genomes(KEGG)and gene ontology(GO)annotation showed that the functional genes of strain SC-1 are involved in pathways including amino acid synthesis,carbon metabolism,genetic information regulation,and environmental stress response.The carbohydrate-active enzymes(CAZy)of this strain were predominantly glycoside hydrolases and glycosyltransferases,indicating that the strain can metabolize carbohydrates.Acid and bile salt tolerance assays demonstrated that the survival rate of SC-1 was(68.89±3.91)％in an acidic environment(pH 2.5)and(50.30±4.25)％at 0.3％(m/m)bile salt content,respectively.In addition,SC-1 exhibited γ-hemolysis(non-hemolytic activity)and it was sensitive to common antibiotics such as penicillin but showed resistance to several aminoglycoside antibiotics.SC-1 had no significant virulence and its resistance genes posed no transfer risk.关键词
植物乳植杆菌/全基因组测序/安全性评价/功能基因Key words
Lactiplantibacillus plantarum/whole genome sequencing/safety evaluation/functional genes分类
轻工纺织引用本文复制引用
伍忠玲..植物乳植杆菌SC-1全基因组测序及安全性评价[J].乳业科学与技术,2026,49(3):11-16,6.基金项目
上海市国资委企业创新发展与能级提升项目(2022013) （2022013）
