CT理论与应用研究2026，Vol.35Issue(5)：869-874,6.DOI:10.15953/j.ctta.2026.158
超高分辨力CT对中耳胆脂瘤骨质破坏诊断效能的验证
Diagnostic Performance of Ultra-high-resolution CT for Detecting Bone Destruction in Middle Ear Cholesteatoma
摘要
Abstract
Objective:Middle ear cholesteatoma is a potentially destructive non-neoplastic lesion that erodes the adjacent bony structures and may lead to intraotologic and intracranial complications.This study evaluated the performance of ultra-high-resolution computed tomography(U-HRCT)in visualizing the bony destruction of intraotologic structures caused by middle ear cholesteatoma,using intraoperative findings as the reference standard,and to analyze its clinical efficacy from a surgical perspective.Methods:A retrospective analysis was performed on the data from 60 patients who were pathologically diagnosed with middle ear cholesteatoma at our hospital between February 2024 and February 2026.All the patients underwent preoperative U-HRCT.The imaging findings were compared with the intraoperative observations,and the sensitivity,specificity,positive predictive value(PPV),negative predictive value(NPV),accuracy,and kappa value of U-HRCT were calculated.Results:The sensitivity of U-HRCT for detecting the bony destruction of the scutum,tegmen tympani,malleus,incus,and semicircular canal wall was greater than 90%in all cases.Its identification of the destruction of the semicircular canal wall agreed perfectly with the intraoperative results(k=1).The detection of the bony erosion involving the scutum,tegmen tympani,and malleus showed excellent consistency with the intraoperative findings(k>0.8),whereas that of the erosion of the incus,stapes,and facial nerve canal achieved good consistency(k>0.6).Conclusion:U-HRCT enables an accurate preoperative assessment of the bony destruction of the ossicles,facial nerve canal,and other structures caused by middle ear cholesteatoma and can assist surgeons in identifying potential high-risk conditions before surgery.关键词
超高分辨力CT/中耳胆脂瘤/听小骨/面神经管Key words
ultra-high-resolution CT/middle ear cholesteatoma/auditory ossicles/facial nerve canal分类
医药卫生引用本文复制引用
杨佳佳,钟业鸣,钱波,嵇洪波,车子刚..超高分辨力CT对中耳胆脂瘤骨质破坏诊断效能的验证[J].CT理论与应用研究,2026,35(5):869-874,6.基金项目
北京市科技计划项目(耳鼻喉双源锥形束计算机体层摄影设备示范应用(Z241100009024020)) （耳鼻喉双源锥形束计算机体层摄影设备示范应用(Z241100009024020）
北京市自然科学基金面上项目(基于U-HRCT的耳科手术面神经损伤风险智能预警关键技术研究(7252281)) （基于U-HRCT的耳科手术面神经损伤风险智能预警关键技术研究(7252281）
国家自然科学基金面上项目(基于医学知识介导的中耳病变超高分辨力CT智能判读关键技术研究(62371316)). （基于医学知识介导的中耳病变超高分辨力CT智能判读关键技术研究(62371316）
