CT理论与应用研究2026，Vol.35Issue(5)：875-886,12.DOI:10.15953/j.ctta.2026.153
基于U-HRCT的内耳亚结构标注规范构建与验证
Construction and Validation of U-HRCT-based Annotation Specifications for Inner Ear Substructures
摘要
Abstract
Objective:Manually annotated data are required for training intelligent segmentation models of computed tomography-scanned inner ear substructures and performing precise measurement of quantitative indicators.To address the high demand for consistency in such data as well as the critical issues of large annotation biases and data fragmentation caused by the lack of standardized annotation protocols,we propose herein a systematic pixel-level annotation specification for inner ear substructures.The purpose of this specification is to resolve the problems of ambiguous boundaries between different substructures and inconsistent manual annotation,thereby facilitating multicenter collaboration and the clinical translation of related technologies.Methods:On the basis of ultra-high-resolution computed tomography(U-HRCT)images,with the lateral semicircular canal used as the calibration reference for aligning the scan slices to the plane of maximum visualization,the bony labyrinth of the inner ear was subdivided into six independent substructures:the cochlea,vestibule,superior semicircular canal(excluding the common crus),lateral semicircular canal,posterior semicircular canal(excluding the common crus),and common crus,with explicit boundary definitions for each structure.A two-level quality control process was implemented in combination with axial-coronal-sagittal three-view verification,and all file formats were standardized.U-HRCT images of inner ears untouched by prior surgery were used in the study.Nineteen annotators with comparable annotation experience were enrolled and divided into a trained group and an untrained group for comparison of their scoring reliability and annotation quality,the results of which were analyzed using correlation coefficient statistics and the Mann-Whitney U test,respectively.Results:The anatomical conformity and annotation quality scores of all substructures were significantly higher in the trained group than in the untrained group,and the inter-expert agreement of evaluation results was favorable.Conclusion:This specification incorporates the common crus as an independent substructure and establishes a pixel-level annotation specification for inner ear substructures.It effectively improves the accuracy of manual annotation,provides high-quality data for training intelligent segmentation models and measuring quantitative parameters,and facilitates multicenter data sharing and the clinical translation of inner ear-related technologies,thus possessing important clinical and scientific research value.关键词
内耳/U-HRCT/手动标注/标注规范/亚结构模型/一致性Key words
inner ear/U-HRCT/manual segmentation/annotation specification/substructure model/consistency分类
医药卫生引用本文复制引用
张晔,杨雪,杨德武,冯懿俐,张景茜,陆文凯,尹红霞..基于U-HRCT的内耳亚结构标注规范构建与验证[J].CT理论与应用研究,2026,35(5):875-886,12.基金项目
北京市科技计划(耳鼻喉双源锥形束计算机体层摄影设备示范应用(Z241100009024020)) （耳鼻喉双源锥形束计算机体层摄影设备示范应用(Z241100009024020）
北京市自然科学基金面上项目(基于U-HRCT的耳科手术面神经损伤风险智能预警关键技术研究(7252281)) （基于U-HRCT的耳科手术面神经损伤风险智能预警关键技术研究(7252281）
国家自然科学基金面上项目(基于医学知识介导的中耳病变超高分辨力CT智能判读关键技术研究(62371316)). （基于医学知识介导的中耳病变超高分辨力CT智能判读关键技术研究(62371316）
