中国食品添加剂2026，Vol.37Issue(8)：53-58,6.DOI:10.19804/j.issn1006-2513.2026.8.006
维药余甘子牛奶炮制工艺优化及其神经细胞保护作用
Optimization of milk-processed Phyllanthus emblica in uyghur medicine and its neuroprotective effects
摘要
Abstract
Abstact:Referencing the traditional uyghur medicine method of soaking Phyllanthus emblica in milk,three batches of emblica decoction pieces were selected.An L9(34)orthogonal test method was used,four factors including milk concentration,material-to-liquid ratio,temperature,and time were investigated by examining the changes in the content of the indicator components gallic acid and vitamin C.This was done to comprehensively screen for the optimal milk-processing technology for emblica.The MTT assay was used to study the pharmacodynamic effects of the processed decoction pieces on the proliferation of PC 12 neural cells.The optimal processing conditions for emblica were determined as follows:100％fresh milk,a material-to-liquid ratio of 1∶5(g/mL),a soaking time of 6 h,and a soaking temperature of 25 ℃.The processed emblica decoction pieces increased the viability of PC 12 cells to 160.06％,showing a significant difference compared to the raw emblica product(P＜0.05).This study standardized the traditional milk-soaking process for emblica,providing a scientific basis for the standardized production and application of emblica decoction pieces.关键词
余甘子奶制备/正交试验/没食子酸/含量测定/神经保护Key words
milk-processed Phyllanthus emblica/orthogonal test/gallic acid/content determination/neuroprotection分类
轻工纺织引用本文复制引用
戴文全,李小燕,马渊印,马芹,苏建霞,刘小倩,王晓敏,陈伟..维药余甘子牛奶炮制工艺优化及其神经细胞保护作用[J].中国食品添加剂,2026,37(8):53-58,6.基金项目
新疆维吾尔自治区重大科技攻关项目(2022A03017-2) （2022A03017-2）
新疆天山英才青年拔尖人才(2022TSYCCY0014) （2022TSYCCY0014）
兵团科技创新人才计划项目(2023CB002) （2023CB002）
师市科技攻关计划项目(2023GG2501) （2023GG2501）
