食品科学2026，Vol.47Issue(19)：344-357,14.DOI:10.7506/spkx1002-6630-20260515-125
全谷物经肠道菌群介导调控黏膜免疫的作用机制及研究进展
Research Advances in the Mechanism for Gut Microbiota-Mediated Regulation of Intestinal Mucosal Immunity by Whole Grains
摘要
Abstract
In recent years,the mechanism underlying the cross-talk between the gut microbiota and host immunity has emerged as a research hotspot in nutritional immunology.Whole grains are rich in diverse bioactive components,including dietary fibers,polyphenols,phytosterols,and resistant starch.These components exert positive effects on the intestinal mucosal immune system by remodeling the gut microbiota,regulating immune cell differentiation,repairing the epithelial barrier,and inhibiting proinflammatory signaling pathways.This review summarizes the bioactive components of whole grains,alterations in the gut microbiota and their metabolites,and the modulation of intestinal mucosal immunity,aiming to provide a theoretical reference for immunonutrition research and clinical application of whole grains.关键词
全谷物/肠道菌群/黏膜免疫/短链脂肪酸/膳食纤维Key words
whole grains/gut microbiota/mucosal immunity/short-chain fatty acids/dietary fiber分类
医药卫生引用本文复制引用
徐旻皓,丁颜,王怡恬,王东旭,于振,郭元新..全谷物经肠道菌群介导调控黏膜免疫的作用机制及研究进展[J].食品科学,2026,47(19):344-357,14.基金项目
国家自然科学基金面上项目(32572539) （32572539）
镇江市科技计划项目(NY2024015) （NY2024015）
