乳腺癌组织 Ki-67与 p53的表达特征及与预后的关系OA
The pattern of Ki-67 and p53 expression in breas t cancer tissue and its correlation to prognosis
目的：分析乳腺癌组织Ki-67与p53的表达特征及其与预后的关系。方法选取70例行乳腺癌根治手术的乳腺肿瘤患者癌组织标本，采用免疫组织化学（Immunohistochemistry，IHC）SP二步染色法检测乳腺癌组织（研究组）及其癌旁组织（对照组）中Ki-67和p53的表达；结合术后随访资料，比较5年内复发转移患者与无复发转移患者的Ki-67、p53表达水平。结果研究组Ki-67、p53蛋白阳性率均显著高于对照组（均P＜0．01）；复发转移组的…查看全部>>
Objective To find out the pattern of the expression of Ki-67 and P53 in breast cancer tissue and its correlation to prognosis.MethodSpecimen of breast cancer tissue was firstly obtained from 70 breast cancer patients having undergone . Immunohistochemistry ( IHC) SPtwo-step staining was then used to detect the expression of Ki -67 and P53 in the cancer tissue ( the control subject ) and the expression of Ki-67 and P53 in the tissue ( the experimental subject…查看全部>>
唐勇民;江四平
常山县人民医院病理科，浙江 常山 324200常山县人民医院外一科，浙江 常山 324200
医药卫生
乳腺癌Ki-67p53预后
breast cancerKi-67P53prognosis
《健康研究》 2015 (6)
624-626,3
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