茶叶科学2024，Vol.44Issue(1)：1-15,15.
多酚自组装抗菌生物材料的构建及其应用进展
Construction of Polyphenol Self-assembly Antibacterial Biomaterials and Progress in Their Applications
摘要
Abstract
Bacterial infection,a leading cause of global mortality,can result in various diseases.While antibiotics are the primary treatment for infections,their excessive and irrational use has led to the emergence of a variety of bacterial drug resistance,posing a serious threat to human health.Plant polyphenols have natural antibacterial properties,but the instability of the phenolic hydroxyl structure limits their bioavailability.To solve this problem,researchers have explored the self-assembly of polyphenols with other substances to construct new nano-biomaterials.These biomaterials not only enhance the stability and bioavailability of polyphenols but also exhibit synergistic antibacterial activity,showing a great promise in the field of antibacterial applications.This review examined the construction strategies and antibacterial properties of different types of polyphenol self-assembled biomaterials developed in recent years,including polyphenol-metal,polyphenol-hydrogel,polyphenol-chitosan,polyphenol-protein and polyphenol-liposome.Furthermore,the challenges and future prospects of the novel polyphenol self-assembling biomaterials in the field of antibacterial application were discussed.关键词
多酚/自组装/纳米材料/抗菌应用Key words
polyphenols/self-assembly/nanomaterials/antibacterial applications分类
农业科技引用本文复制引用
徐伟,韦兵,俞蓉欣,张相春,张以稳,陈红平,田宝明,郑芹芹,吴媛媛,夏琛..多酚自组装抗菌生物材料的构建及其应用进展[J].茶叶科学,2024,44(1):1-15,15.基金项目
浙江省重点研发计划(2023C02040、2022C04036)、国家自然科学基金(32372757、52003053)、中国农业科学院创新工程(CAAS-ASTIP-2021-TRI)、国家茶叶产业技术体系(CARS-19) （2023C02040、2022C04036）
