中国医疗设备2024，Vol.39Issue(3)：1-6,19,7.DOI:10.3969/j.issn.1674-1633.2024.03.001
气道异物淤积导致呼吸波形改变的临床模拟研究
Clinical Simulation of Airway Obstruction Leading to Altered Respiratory Waveforms
摘要
Abstract
Objective By carrying out clinical simulation on altered respiratory waveforms caused by airway obstruction,to establish the relationship between airway obstruction and the degree of altered respiratory waveforms,and verify the feasibility of real-time visual monitoring of airways.Methods A respiratory simulation platform with controllable airway obstruction was built to collect the corresponding respiratory waveforms under different airway obstruction.Waveform features were extracted,the coefficient of variation,correlation coefficient and rms error were calculated,and the fitting relationship curve between the airway obstruction and the respiratory waveform features was established based on the least square method.Results The rising peak,ascending gradient and falling peak of the flow rate waveform in pressure-controlled ventilation mode and volume-controlled ventilation mode were strongly correlated with the airway obstruction,and the correlation could be described by quadrics.Conclusion The quantitative description of the relationship between airway obstruction and respiratory waveform characteristics verifies the feasibility of real-time visual monitoring of airways,and provides a new idea for artificial airway management.关键词
气道阻塞/呼吸波形/临床模拟研究/最小二乘法/拟合曲线Key words
airway obstruction/respiratory waveforms/clinical simulation/least square method/fitted curve分类
医药卫生引用本文复制引用
熊伟,毛彬,陈寒鉴,黄永全,王彬权,孙静,张倩,冯靖祎..气道异物淤积导致呼吸波形改变的临床模拟研究[J].中国医疗设备,2024,39(3):1-6,19,7.基金项目
浙江省医药卫生科研面上项目资助(2021KY685) （2021KY685）
浙江省"尖兵""领雁"研发攻关计划(2022C03147) （2022C03147）
浙江省自然科学基金(LQ21H180009) （LQ21H180009）
浙江省自然科学基金(LQ20C100001). （LQ20C100001）
