注意缺陷多动障碍患儿大脑皮质结构异常研究进展OA北大核心CSTPCD
Progress on structural abnormalities in the cerebral cortex in children with attention deficit/hyperactivity disorder
神经影像学技术在注意缺陷多动障碍(ADHD)研究领域的应用日趋广泛,越来越多研究表明ADHD患者存在皮质体积减少、厚度变薄、表面积降低等结构异常,这些结构异常与患者复杂的临床症状及大脑功能异常具有一定相关性.然而使用神经影像技术识别生物标志物作为ADHD的客观诊断工具仍面临诸多挑战.多模态研究来探讨ADHD患者不同脑区结构与功能的关系,利用神经影像学揭示ADHD患者整个生命周期临床症状演变的机制可作为未来研究的重要方向.
Neuroimaging is increasingly widely used in the field of ADHD research,and more and more studies have shown that ADHD patients have structural abnormalities such as reduced cortical volume,thinning thickness,and reduced surface area,which are related to complex clinical symptoms and abnormal brain function in patients.However,the use of neuroimaging to identify biomarkers as an objective diagnostic tool for ADHD still faces many challenges.Multimodal studies can be used to explore the relationship between the structure and function of different brain regions in ADHD patients,and to use neuroimaging to reveal the mechanism of the evolution of clinical symptoms in the whole life cycle of ADHD patients.
袁海霞;韩新民;陈天翼;宋宇尘
南京中医药大学附属医院儿科(南京 210029)南京中医药大学中西医结合学院(南京 210023)
临床医学
注意缺陷多动障碍皮质结构异常研究进展
attention deficit/hyperactivity disordercortexstructural abnormalitiesresearch progress
《实用医学杂志》 2024 (010)
1455-1459 / 5
国家自然科学基金项目(编号:82004416,82205180);江苏省高等学校自然科学基金面上项目(编号:20KJB360001);南京中医药大学自然科学基金青年项目(编号:NZY82004416,XPT82205180);江苏省中医院优秀青年博士培养计划(编号:2023QB0135)
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