茶儿茶素稳定血糖作用及机理研究进展OA北大核心CSTPCD
Research Progress on Glycemic Control Effect and Mechanism of Tea Catechins
随着现代社会饮食结构的变化,糖尿病及其并发症已成为全球关注的公共卫生问题,中国患病总人数已位居世界第一.现代科学证明茶叶是降血糖天然多酚的重要来源,作为健康饮品在糖尿病膳食治疗中发挥重要作用.儿茶素是茶叶中关键功能物质,能够通过抑制外源碳水化合物水解、调控葡萄糖转移、促进葡萄糖氧化分解、抑制糖异生过程、调控糖原合成及分解过程、促进胰岛素分泌、改善胰岛素抵抗、改善氧化应激状态等不同途径有效调节血糖水平.本文在总结国内外有关儿茶素对肥胖、糖尿病及代谢综合症作用研究的基础上,梳理了儿茶素稳定血糖生理机制的研究进展,旨在为儿茶素的精准化开发提供理论依据及应用参考.
As people's diet structure changes in modern society,diabetes and its complications have become a global public health concern.China has the world's largest number of diabetics.Modern science has proved that tea is an important source of natural hypoglycemic polyphenols and plays an important role in the dietary treatment of diabetes as a healthy drink.Tea catechins are the key functional substances in tea,which can effectively regulate blood glucose levels through various pathways,such as inhibiting exogenous carbohydrate hydrolysis,regulating glucose transfer,promoting oxidative decomposition of glucose,inhibiting gluconeogenesis,regulating glycogen synthesis and decomposition,promoting insulin secretion,rescuing insulin resistance and reducing oxidative stress status.Beginning with a summary of recent studies on the effects of tea catechins on obesity,diabetes and metabolic syndromes,this paper moves on to review the latest knowledge on the physiological mechanism of blood glucose stabilization by tea catechins,hoping to provide a theoretical basis for the precise development and application of tea catechins.
汪凌辉;许娜;杨倩楠;黄进宝;王一君;宛晓春
安徽农业大学茶与食品科技学院,安徽合肥 230036安徽农业大学茶与食品科技学院,安徽合肥 230036||安徽农业大学茶树生物学与资源利用国家重点实验室,安徽合肥 230036
农业科学
茶儿茶素血糖糖代谢糖尿病胰岛素抵抗
tea catechinsblood glucoseglucose metabolismdiabetesinsulin resistance
《食品科学》 2024 (010)
330-341 / 12
"十四五"国家重点研发计划重点专项(2021YFD1601102);安徽省高校自然科学重点项目(2022AH050894);安徽省研究生教育质量工程项目(2022jyjxggyj194)
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