桑蚕蛋白复合粉抗运动疲劳功效研究OACSTPCD

To study the anti-fatigue effects of silkworm protein complex powder and the underlying mechanisms,C57BL/6 male mice were divided into a control group,a low dose group(50 mg/kg·d),a medium dose group(100 mg/kg·d)and a high dose group(200 mg/kg·d).After 30 days of gavage,exhaustive swimming time and movement fatigue biochemical markers(blood urea nitrogen,blood lactic acid,muscular lactic acid,liver glycogen,muscle glycogen,and the activity of antioxidant-related enzymes in skeletal muscle)were tested.Compared with the control group,the exhaustive swimming time in the silkworm protein complex powder groups was significantly prolonged,the levels of blood urea nitrogen,muscular lactic acid and blood lactic acid were significantly decreased,the contents of liver glycogen and muscle glycogen were significantly increased,the total antioxidant capacity and the activity of glutathione peroxidase,superoxide dismutase,catalase in skeletal muscle were significantly elevated,and the level of malondialdehyde was significantly decreased.The silkworm protein complex powder exerted anti-exercise fatigue effects of mice by reducing the accumulation of lactic acid,muscular lactic acid and blood urea nitrogen,increasing the storage of liver glycogen and muscle glycogen,and alleviating the oxidative stress of skeletal muscle.