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孕期传统和新兴真菌毒素暴露的胚胎发育毒性及其生物监测的研究现状

韩小敏 叶金 纪剑 徐文静 吴宇 叶永丽 Rudolf KRSKA 孙秀兰 白莉

粮油食品科技2024,Vol.32Issue(4):16-23,8.
粮油食品科技2024,Vol.32Issue(4):16-23,8.DOI:10.16210/j.cnki.1007-7561.2024.04.002

孕期传统和新兴真菌毒素暴露的胚胎发育毒性及其生物监测的研究现状

Research Status of Embryonic Developmental Toxicity and Biological Monitoring of Exposure to Traditional and Emerging Mycotoxins during Pregnancy

韩小敏 1叶金 2纪剑 3徐文静 1吴宇 2叶永丽 3Rudolf KRSKA 4孙秀兰 3白莉1

作者信息

  • 1. 国家食品安全风险评估中心,北京 100022
  • 2. 国家粮食和物资储备局科学研究院 粮油质量安全研究所,北京 100037
  • 3. 江南大学 食品学院,江苏 无锡 214122
  • 4. 维也纳自然资源与生命科学大学,生物分析与农业代谢组学研究所,农业生物技术系,奥地利,图尔恩 3430||贝尔法斯特女王大学,生物科学学院,全球食品安全研究所,英国,北爱尔兰 贝尔法斯特 BT9 5DL
  • 折叠

摘要

Abstract

Mycotoxins are toxic secondary metabolites produced by certain fungal species under specific conditions.Research has found that exposure to various fungal toxins can cause embryonic developmental toxicity,such as embryo arrest,abortion,and intrauterine fetal developmental delay.There are no systematic reports on the impact of exposure to fungal toxins during pregnancy on the toxicity of intrauterine fetal development and biological monitoring.Therefore,in order to prevent and reduce the harm of fungal toxins during pregnancy,this paper summarizes the research status of embryonic developmental toxicity,as well as the research status of biological monitoring technologies based on biomarkers such as exposure biomarkers and biomakers of effect,which are caused by traditional fungal toxins such as aflatoxin,deoxynivalenol,zearalenone,and emerging fungal toxins such as Alternaria toxins,beauverin,and enniatins.The aim of the paper is for construction of the healthy China.

关键词

孕期/传统和新兴真菌毒素/胚胎发育毒性/生物监测

Key words

pregnancy/traditional and emerging mycotoxin/embryo developmental toxicity/biological monitoring

分类

轻工纺织

引用本文复制引用

韩小敏,叶金,纪剑,徐文静,吴宇,叶永丽,Rudolf KRSKA,孙秀兰,白莉..孕期传统和新兴真菌毒素暴露的胚胎发育毒性及其生物监测的研究现状[J].粮油食品科技,2024,32(4):16-23,8.

基金项目

国家重点研发计划项目(2022YFE0137500) (2022YFE0137500)

北京市自然科学基金面上项目(7212145) National Key Research and Development Program of China(No.2022YFE0137500) (7212145)

Beijing Natural Science Foundation Project(No.7212145) (No.7212145)

粮油食品科技

OA北大核心CSTPCD

1007-7561

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