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- 中国科学引文数据库(CSCD)（21）
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- 药物分析学报:英文版（44）
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- Xiaohui Fan（4）
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- Single-cell RNA-sequencing and subcellular spatial transcriptomics facilitate the translation of liver microphysiological systems for regulatory applicationCSCD摘要：Reducing the use of animal models in drug development and safety assessment has long been supported by the U.S.Food and Drug Administration(FDA).The report by Royal Society for the Prevention of Cruelty to Animals indic…查看全部>>
- Preface for Special Issue: Single-Cell and Spatially Resolved OmicsCSCD摘要：In this special issue,we are excited to present a collection of articles focusing on the emerging and rapidly evolving field of singlecell and spatially resolved omics,including epigenomics,transcriptomics,proteomics…查看全部>>
- Inhibition of histone methyltransferase PRMT5 attenuates cisplatininduced hearing loss through the PI3K/Akt-mediated mitochondrial apoptotic pathwayProtein arginine methyltransferase 5(PRMT5)LLY-283CisplatinHearing lossHair cellSpiral ganglion neuron摘要：This study aimed to evaluate the therapeutic potential of inhibiting protein arginine methyltransferase 5(PRMT5)in cisplatin-induced hearing loss.The effects of PRMT5 inhibition on cisplatin-induced auditory injury were…查看全部>>
- Cocktail hepatocarcinoma therapy by a super-assembled nano-pill targeting XPO1 and ATR synergistically摘要：Intensive cancer treatment with drug combination is widely exploited in the clinic but suffers from inconsistent pharmacokinetics among different therapeutic agents.To overcome it,the emerging nanomedicine offers an …查看全部>>
- Breath-by-breath measurement of exhaled ammonia by acetonemodifier positive photoionization ion mobility spectrometry via online dilution and purging sampling摘要：Exhaled ammonia(NH_(3))is an essential noninvasive biomarker for disease diagnosis.In this study,an acetone-modifier positive photoionization ion mobility spectrometry(AM-PIMS)method was developed for accurate qualit…查看全部>>
- Single-cell transcriptome analysis uncovers underlying mechanisms of acute liver injury induced by tripterygium glycosides tablet in miceCSCD摘要：Tripterygium glycosides tablet(TGT),the classical commercial drug of Tripterygium wilfordii Hook.F.has been effectively used in the treatment of rheumatoid arthritis,nephrotic syndrome,leprosy,Behcet’s syndrome,leprosy …查看全部>>
- The role of signaling crosstalk of microglia in hippocampus on progression of ageing and Alzheimer''''s diseaseCSCD摘要：Based on single-cell sequencing of the hippocampi of 5×familiar Alzheimer’s disease(5×FAD)and wild type mice at 2-,12-,and 24-month of age,we found an increased percentage of microglia in aging and Alzheimer’s disease(A…查看全部>>
- Novel wine in an old bottle:Preventive and therapeutic potentials of andrographolide in atherosclerotic cardiovascular diseasesAndrographolideAtherosclerosisAtherosclerotic cardiovascular diseasePharmacological effectsPharmacokinetics propertiesToxicity摘要：Atherosclerotic cardiovascular disease(ASCVD)frequently results in sudden death and poses a serious threat to public health worldwide.The drugs approved for the prevention and treatment of ASCVD are usually used in comb…查看全部>>
- Recent progress in aptamer-based microfluidics for the detection of circulating tumor cells and extracellular vesicles摘要：Liquid biopsy is a technology that exhibits potential to detect cancer early,monitor therapies,and predict cancer prognosis due to its unique characteristics,including noninvasive sampling and real-time analysis.Circula…查看全部>>
- Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsisCSCD摘要：Sepsis is characterized by a severe and life-threatening host immune response to polymicrobial infection accompanied by organ dysfunction.Studies on the therapeutic effect and mechanism of immunomodulatory drugs on the …查看全部>>