- 年份
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- 中国科学引文数据库(CSCD)（21）
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- 药物分析学报:英文版（44）
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- Xiaohui Fan（4）
- Guangqing Cheng（3）
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- Jiayun Chen（2）
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- Single-cell and spatially resolved omics:Advances and limitationsCSCD摘要：Recent advances in experimental and computational single-cell and spatially resolved omics have opened new avenues for research in biology and medicine.These technologies allow for the study of individual cells in un…查看全部>>
- Preface for Special Issue: Single-Cell and Spatially Resolved OmicsCSCD摘要：In this special issue,we are excited to present a collection of articles focusing on the emerging and rapidly evolving field of singlecell and spatially resolved omics,including epigenomics,transcriptomics,proteomics…查看全部>>
- Single-cell RNA sequencing reveals the dynamics of hepatic non-parenchymal cells in autoprotection against acetaminophen-induced hepatotoxicityCSCDSingle-cell RNA sequencingDrug-induced liver injuryAutoprotection against APAP hepatotoxicityEndothelial cellsDendritic cells摘要：Gaining a better understanding of autoprotection against drug-induced liver injury(DILI)may provide new strategies for its prevention and therapy.However,little is known about the underlying mechanisms of this phenomeno…查看全部>>
- Integrative multi-omics and systems bioinformatics in translational neuroscience:A data mining perspectiveCSCDMulti-omics integrationSystems bioinformaticsData miningHuman brain profile reconstructionTranslational neuroscience摘要：Bioinformatic analysis of large and complex omics datasets has become increasingly useful in modern day biology by providing a great depth of information,with its application to neuroscience termed neuroinformatics.Data…查看全部>>
- Preface for Special Issue:Single-Cell and Spatially Resolved OmicsCSCD摘要：We are delighted to present you this special issue,which consists of a collection of articles focusing on the novel and rapidly evolving field of single-cell and spatially resolved omics.This encompasses epigenomics,…查看全部>>
- Inhibition of histone methyltransferase PRMT5 attenuates cisplatininduced hearing loss through the PI3K/Akt-mediated mitochondrial apoptotic pathwayProtein arginine methyltransferase 5(PRMT5)LLY-283CisplatinHearing lossHair cellSpiral ganglion neuron摘要：This study aimed to evaluate the therapeutic potential of inhibiting protein arginine methyltransferase 5(PRMT5)in cisplatin-induced hearing loss.The effects of PRMT5 inhibition on cisplatin-induced auditory injury were…查看全部>>
- Cocktail hepatocarcinoma therapy by a super-assembled nano-pill targeting XPO1 and ATR synergistically摘要：Intensive cancer treatment with drug combination is widely exploited in the clinic but suffers from inconsistent pharmacokinetics among different therapeutic agents.To overcome it,the emerging nanomedicine offers an …查看全部>>
- Single-cell transcriptome analysis uncovers underlying mechanisms of acute liver injury induced by tripterygium glycosides tablet in miceCSCD摘要：Tripterygium glycosides tablet(TGT),the classical commercial drug of Tripterygium wilfordii Hook.F.has been effectively used in the treatment of rheumatoid arthritis,nephrotic syndrome,leprosy,Behcet’s syndrome,leprosy …查看全部>>
- The role of signaling crosstalk of microglia in hippocampus on progression of ageing and Alzheimer''''s diseaseCSCD摘要：Based on single-cell sequencing of the hippocampi of 5×familiar Alzheimer’s disease(5×FAD)and wild type mice at 2-,12-,and 24-month of age,we found an increased percentage of microglia in aging and Alzheimer’s disease(A…查看全部>>
- Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsisCSCD摘要：Sepsis is characterized by a severe and life-threatening host immune response to polymicrobial infection accompanied by organ dysfunction.Studies on the therapeutic effect and mechanism of immunomodulatory drugs on the …查看全部>>